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Evolving a robust signal transduction pathway from weak cross-talk
We have evolved a robust two-component signal transduction pathway from a sensor kinase (SK) and non-partner response regulator (RR) that show weak cross-talk in vitro and no detectable cross-talk in vivo in wild-type strains. The SK, CpxA, is bifunctional, with both kinase and phosphatase activitie...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018164/ https://ncbi.nlm.nih.gov/pubmed/21179024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.105 |
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