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Platelet hypersensitivity induced by cholesterol incorporation.

Platelets from individuals with familial hypercholesterolemia show increased sensitivity to the aggregating atents, epinephrine and ADP. Since the mechanism of this abnormal sensitivity is unknown, we examined, in vitro, the influence of the plasma lipid environment on the function of platelets. The...

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Detalhes bibliográficos
Main Authors: Shattil, S J, Anaya-Galindo, R, Bennett, J, Colman, R W, Cooper, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC301792/
https://ncbi.nlm.nih.gov/pubmed/1117069
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