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Biosynthesis of bile acids in man. Hydroxylation of the C27-steroid side chain.

The first step in the degradation of the steroid side chain during biosynthesis of bile acids from cholesterol in man was studied in microsomal and mitochondrial fraction of homogenate of livers from 14 patients. The microsomal fraction was found to catalyze an efficient 25-hydroxylation of 5,8-chol...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Björkhem, I, Gustafsson, J, Johansson, G, Persson, B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1975
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1117065/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107954
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