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Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia.

We have used a continuous intravenous infusion of glucose (6 mg/kg/min), insulin (80 mU/min), epinephrine (6 mug/min), and propranolol (0.08 mg/min) to directly assess insulin resistance in 14 untreated adult onset diabetics with a mean (plus or minus SE) fasting plasma glucose level of 217 plus or...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Ginsberg, H, Kimmerling, G, Olefsky, J M, Reaven, G M
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1975
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1117064/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107951
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