Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages

Tumor necrosis factor receptor (TNFR) p55-knockout (KO) mice are susceptible profoundly to Salmonella infection. One day after peritoneal inoculation, TNFR-KO mice harbor 1,000-fold more bacteria in liver and spleen than wild-type mice despite the formation of well organized granulomas. Macrophages...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Vázquez-Torres, Andrés, Fantuzzi, Giamila, Edwards, Carl K., Dinarello, Charles A., Fang, Ferric C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041618998
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