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Sphingosine 1-phosphate and immune regulation: trafficking and beyond
Sphingosine 1-phosphate (S1P) is a bioactive lipid with important functions in the immune system. S1P levels are regulated by the balance between its synthesis through sphingosine kinases and its degradation by the S1P lyase. S1P signals through plasma membrane G protein-coupled receptors (S1P(1) –...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017656/ https://ncbi.nlm.nih.gov/pubmed/21159389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2010.11.002 |
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