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Efficient use of accessibility in microRNA target prediction

Considering accessibility of the 3′UTR is believed to increase the precision of microRNA target predictions. We show that, contrary to common belief, ranking by the hybridization energy or by the sum of the opening and hybridization energies, used in currently available algorithms, is not an efficie...

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Detalhes bibliográficos
Main Authors: Marín, Ray M., Vaníček, Jiří
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017612/
https://ncbi.nlm.nih.gov/pubmed/20805242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq768
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