β-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices

BACKGROUND: Inflammation acting in synergy with brain ischemia aggravates perinatal ischemic brain damage. The sensitizing effect of pro-inflammatory exposure prior to hypoxia is dependent on signaling by TNF-α through TNF receptor (TNFR) 1. Adrenoceptor (AR) activation is known to modulate the immu...

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Detalhes bibliográficos
Main Authors: Markus, Tina, Hansson, Stefan R, Cronberg, Tobias, Cilio, Corrado, Wieloch, Tadeusz, Ley, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017519/
https://ncbi.nlm.nih.gov/pubmed/21172031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-94
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