A multiple-dose pharmacokinetics of polyethylene glycol recombinant human interleukin-6 (PEG-rhIL-6) in rats

Radiation therapy has been widely applied in cancer treatment. However, it often causes thrombocytopenia (deficiency of white blood cells) as an adverse effect. Recombinant human interleukin-6 (rhIL-6) has been found to be a very effective way against this thrombocytopenia, but IL-6 has low stabilit...

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Bibliographic Details
Main Authors: He, Xue-ling, Yin, Hai-lin, Wu, Jiang, Zhang, Ke, Liu, Yan, Yuan, Tao, Rao, Hai-lin, Li, Liang, Yang, Guang, Zhang, Xue-mei
Format: Artigo
Language:Inglês
Published: Zhejiang University Press 2011
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017414/
https://ncbi.nlm.nih.gov/pubmed/21194184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1000085
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