Inhibition of hormone-stimulated lipolysis by clofibrate. A possible mechanism for its hypolipidemic action.
The present study was undertaken to investigate the mechanism of the antilipolytic action of clofibrate (p-chlorophenoxyisobutyrate). Clofibrate, in the dose range of 10-80 mg/199 ml, inhibited the initial rate of norepinephrine-stimulated lipolysis 17-44 percent in isolated rat fat cells. At a dose...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1975
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/162783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107904 |
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