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Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse

Cocaine addiction remains without an effective pharmacotherapy and is characterized by an inability of addicts to inhibit relapse to drug use. Vulnerability to relapse arises from an enduring impairment in cognitive control of motivated behavior, manifested in part by dysregulated synaptic potentiat...

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Hlavní autoři: Moussawi, Khaled, Zhou, Wenhua, Shen, Haowei, Reichel, Carmela M., See, Ronald E., Carr, David B., Kalivas, Peter W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017187/
https://ncbi.nlm.nih.gov/pubmed/21173236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011265108
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