Defective anchoring of JNK1 in the cytoplasm by MKK7 in Jurkat cells is associated with resistance to Fas-mediated apoptosis

The c-Jun N-terminal protein kinase (JNK) plays a context-dependent role in tumorigenesis. Stress-induced redistribution of JNK from the cytoplasm to the nucleus has been demonstrated as essential for stress-induced cell death. However, accumulation of basal JNK activity in the nucleus has frequentl...

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Hauptverfasser: Wang, Jing, Tang, Ruihong, Lv, Ming, Wang, Qingyang, Zhang, Xueying, Guo, Yuanyuan, Chang, Hong, Qiao, Chunxia, Xiao, He, Li, Xinying, Li, Yan, Shen, Beifen, Zhang, Jiyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016969/
https://ncbi.nlm.nih.gov/pubmed/21148294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-06-0492
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