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Competitive Binding of Bilirubin and Drugs to Human Serum Albumin Studied by Enzymatic Oxidation
The mechanism of drug-induced displacement of bilirubin from the blood into tissues was studied. A model of simple, competitive binding of bilirubin and drug to one site on serum albumin was established. Variations of the free bilirubin concentration after addition of drugs were studied in vitro by...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1974
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC301690/ https://ncbi.nlm.nih.gov/pubmed/4436437 |
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