Dimethoxycurcumin, a Structural Analogue of Curcumin, Induces Apoptosis in Human Renal Carcinoma Caki Cells Through the Production of Reactive Oxygen Species, the Release of Cytochrome c, and the Activation of Caspase-3

PURPOSE: Curcumin (Cur) has been reported to induce apoptosis in human renal carcinoma Caki cells. Dimethoxycurcumin (DMC), one of several synthetic Cur analogues, has been reported to have increased metabolic stability over Cur. We determined whether DMC, like Cur, induces apoptosis in Caki cells a...

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Detalhes bibliográficos
Main Authors: Lee, Jea Whan, Hong, Hye Min, Kwon, Dong Deuk, Pae, Hyun-Ock, Jeong, Hee Jong
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Urological Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016435/
https://ncbi.nlm.nih.gov/pubmed/21221209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4111/kju.2010.51.12.870
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