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PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling

BACKGROUND: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified over the years, it is not always clear which functions or interactions are operative in a particular tumor. This is confou...

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Bibliographic Details
Main Authors: Bebek, Gurkan, Patel, Vishal, Chance, Mark R
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016410/
https://ncbi.nlm.nih.gov/pubmed/21144021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-596
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