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Lack of Trehalose Accelerates H(2)O(2)-Induced Candida albicans Apoptosis through Regulating Ca(2+) Signaling Pathway and Caspase Activity
Trehalose is a non-reducing disaccharide and can be accumulated in response to heat or oxidative stresses in Candida albicans. Here we showed that a C. albicans tps1Δ mutant, which is deficient in trehalose synthesis, exhibited increased apoptosis rate upon H(2)O(2) treatment together with an increa...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3016397/ https://ncbi.nlm.nih.gov/pubmed/21246042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015808 |
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