Hepatitis B Virus Lacks Immune Activating Capacity, but Actively Inhibits Plasmacytoid Dendritic Cell Function

Chronic hepatitis B virus (HBV) infection is caused by inadequate anti-viral immunity. Activation of plasmacytoid dendritic cells (pDC) leading to IFNα production is important for effective anti-viral immunity. Hepatitis B virus (HBV) infection lacks IFNα induction in animal models and patients and...

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Detalhes bibliográficos
Main Authors: Woltman, Andrea M., Op den Brouw, Marjoleine L., Biesta, Paula J., Shi, Cui C., Janssen, Harry L. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016396/
https://ncbi.nlm.nih.gov/pubmed/21246041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015324
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