Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer

BACKGROUND: Immunohistochemistry (IHC) with mutation-specific antibodies may be an ancillary method of detecting EGFR mutations in lung cancer patients. METHODS: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non-small-cell lung cancer (NSCLC) cell lines and t...

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Autori principali: Simonetti, Sara, Molina, Miguel Angel, Queralt, Cristina, de Aguirre, Itziar, Mayo, Clara, Bertran-Alamillo, Jordi, Sanchez, José Javier, Gonzalez-Larriba, Jose Luis, Jimenez, Ulpiano, Isla, Dolores, Moran, Teresa, Viteri, Santiago, Camps, Carlos, Garcia-Campelo, Rosario, Massuti, Bartomeu, Benlloch, Susana, y Cajal, Santiago Ramon, Taron, Miquel, Rosell, Rafael
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016260/
https://ncbi.nlm.nih.gov/pubmed/21167064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-135
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