LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives

Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates. Low-density lipoprotein receptor (LDLR) associated familial hypercholesterolemia (FH) is the most frequent Mendelian disorder and is a...

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Detalhes bibliográficos
Main Authors: Al-Allaf, Faisal A, Coutelle, Charles, Waddington, Simon N, David, Anna L, Harbottle, Richard, Themis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016243/
https://ncbi.nlm.nih.gov/pubmed/21144047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-7682-3-36
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