Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors

Purpose Telatinib is an orally active small-molecule tyrosine kinase inhibitor of kinase insert domain receptor (KDR; VEGFR-2) and fms-related tyrosine kinase 4 (FLT4; VEGFR-3). This study aims at the identification of relationships between single nucleotide polymorphisms (SNPs) in genes encoding fo...

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Detalhes bibliográficos
Main Authors: Steeghs, Neeltje, Gelderblom, Hans, Wessels, Judith, Eskens, Ferry A. L. M., de Bont, Natasja, Nortier, Johan W. R., Guchelaar, Henk-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Phase I Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016151/
https://ncbi.nlm.nih.gov/pubmed/19924384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-009-9347-0
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