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Identification of the endogenous smooth muscle myosin phosphatase-associated kinase

Ca(2+) sensitization of smooth muscle contraction involves inhibition of myosin light chain phosphatase (SMPP-1M) and enhanced myosin light chain phosphorylation. Inhibition of SMPP-1M is modulated through phosphorylation of the myosin targeting subunit (MYPT1) by either Rho-associated kinase (ROK)...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: MacDonald, Justin A., Borman, Meredith A., Murányi, Andrea, Somlyo, Avril V., Hartshorne, David J., Haystead, Timothy A. J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30153/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11226254/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041331498
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