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Immune Complexes Containing Citrullinated Fibrinogen Co-Stimulate Macrophages via Toll-like receptor 4 and Fcγ receptor
OBJECTIVE: RA is associated with the presence of anti-citrullinated protein antibodies (ACPA). Nearly two thirds of patients with ACPA-positive RA have immune complexes (IC) that contain citrullinated fibrinogen (cFb), and these cFb-containing IC (cFb-IC) can exacerbate disease in murine models of R...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3015008/ https://ncbi.nlm.nih.gov/pubmed/20954191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30081 |
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