Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase

BACKGROUND: The biotechnology industry has extensively exploited Escherichia coli for producing recombinant proteins, biofuels etc. However, high growth rate aerobic E. coli cultivations are accompanied by acetate excretion i.e. overflow metabolism which is harmful as it inhibits growth, diverts val...

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Detaylı Bibliyografya
Asıl Yazarlar: Valgepea, Kaspar, Adamberg, Kaarel, Nahku, Ranno, Lahtvee, Petri-Jaan, Arike, Liisa, Vilu, Raivo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014970/
https://ncbi.nlm.nih.gov/pubmed/21122111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-166
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