Human blood and marrow side population stem cell and Stro-1 positive bone marrow stromal cell numbers decline with age, with an increase in quality of surviving stem cells: Correlation with cytokines

Hematological deficiencies increase with aging leading to anemias, reduced hematopoietic stress responses and myelodysplasias. This study tested the hypothesis that side population hematopoietic stem cells (SP-HSC) would decrease with aging, correlating with IGF-1 and IL-6 levels and increases in bo...

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Detalhes bibliográficos
Main Authors: Brusnahan, S.K., McGuire, T.R., Jackson, J.D., Lane, J.T., Garvin, K.L., O’Kane, B.J., Berger, A.M., Tuljapurkar, S.R., Kessinger, M.A., Sharp, J.G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014682/
https://ncbi.nlm.nih.gov/pubmed/21035480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2010.10.002
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