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PIPKIγ90 negatively regulates LFA-1 mediated adhesion and activation in antigen-induced CD4+ T cells
T cell activation requires the formation and maintenance of stable interactions between T cells and antigen presenting cells (APC). The formation of stable T cell-APC contacts depends on the activation of the integrin, LFA-1 (CD11aCD18). Several positive regulators of LFA-1 activation downstream of...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014605/ https://ncbi.nlm.nih.gov/pubmed/20855869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001445 |
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