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PIPKIγ90 negatively regulates LFA-1 mediated adhesion and activation in antigen-induced CD4+ T cells

T cell activation requires the formation and maintenance of stable interactions between T cells and antigen presenting cells (APC). The formation of stable T cell-APC contacts depends on the activation of the integrin, LFA-1 (CD11aCD18). Several positive regulators of LFA-1 activation downstream of...

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Bibliografski detalji
Glavni autori: Wernimont, Sarah A, Legate, Kyle R, Simonson, William TN, Fassler, Reinhard, Huttenlocher, Anna
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014605/
https://ncbi.nlm.nih.gov/pubmed/20855869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001445
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