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ROLE OF HEPATOCYTE NUCLEAR FACTOR 4α IN CONTROLLING COPPER-RESPONSIVE TRANSCRIPTION

Previous global transcriptome and interactome analyses of copper-treated HepG2 cells identified hepatocyte nuclear factor 4α (HNF4α) as a potential master regulator of copper-responsive transcription. Copper exposure caused a decrease in the expression of HNF4α at both mRNA and protein levels, which...

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Détails bibliographiques
Auteurs principaux: Song, Min Ok, Freedman, Jonathan H.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014409/
https://ncbi.nlm.nih.gov/pubmed/20875833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.09.009
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