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Identification of a Systemic Lupus Erythematosus Susceptibility Locus at 11p13 between PDHX and CD44 in a Multiethnic Study

Systemic lupus erythematosus (SLE) is considered to be the prototypic autoimmune disease, with a complex genetic architecture influenced by environmental factors. We sought to replicate a putative association at 11p13 not yet exceeding genome-wide significance (p < 5 × 10(−8)) identified in a gen...

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Autors principals: Lessard, Christopher J., Adrianto, Indra, Kelly, Jennifer A., Kaufman, Kenneth M., Grundahl, Kiely M., Adler, Adam, Williams, Adrienne H., Gallant, Caroline J., Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan A., Brown, Elizabeth E., Chang, Deh-Ming, Criswell, Lindsey A., Edberg, Jeffrey C., Freedman, Barry I., Gregersen, Peter K., Gilkeson, Gary S., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Kimberly, Robert P., Martin, Javier, Merrill, Joan T., Niewold, Timothy B., Park, So-Yeon, Petri, Michelle A., Pons-Estel, Bernardo A., Ramsey-Goldman, Rosalind, Reveille, John D., Song, Yeong Wook, Stevens, Anne M., Tsao, Betty P., Vila, Luis M., Vyse, Timothy J., Yu, Chack-Yung, Guthridge, Joel M., Bruner, Gail R., Langefeld, Carl D., Montgomery, Courtney, Harley, John B., Scofield, R. Hal, Gaffney, Patrick M., Moser, Kathy L.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014359/
https://ncbi.nlm.nih.gov/pubmed/21194677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.11.014
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