Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity

Tie-2 is a member of the receptor tyrosine kinase family and is required for vascular remodeling and maintenance of mammalian vessel integrity. A number of mutations in the human TIE2 gene have been identified in patients suffering from cutaneomucosal venous malformations and ventricular septal defe...

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Detaylı Bibliyografya
Asıl Yazarlar: Gjini, Evisa, Hekking, Liesbeth H., Küchler, Axel, Saharinen, Pipsa, Wienholds, Erno, Post, Jan-Andries, Alitalo, Kari, Schulte-Merker, Stefan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Limited 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014345/
https://ncbi.nlm.nih.gov/pubmed/21045210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.005033
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