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Gene expression profiling of TGFβ2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-β2 signaling
A distinct structural change in the trabecular meshwork (TM) of patients with primary open-angle glaucoma (POAH) is the increase in fibrillar extracellular matrix (ECM) in the juxtacanalicular region of the TM. Transforming growth factor (TGF)-β2 signaling may be involved, as TGF-β2 is significantly...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014319/ https://ncbi.nlm.nih.gov/pubmed/19450457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.01.002 |
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