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Novel F141L Pre-S2 Mutation in Hepatitis B Virus Increases the Risk of Hepatocellular Carcinoma in Patients with Chronic Genotype C Infections

Several lines of evidence have suggested that some naturally occurring mutations of hepatitis B virus (HBV) play a critical role in hepatocellular carcinoma (HCC). Here, we describe a novel HCC-related pre-S2 mutation, F141L. To prove the relationship between the F141L mutation and HCC, molecular ep...

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Detalhes bibliográficos
Main Authors: Mun, Ho-Suk, Lee, Seoung-Ae, Kim, Hong, Hwang, Eung-Soo, Kook, Yoon-Hoh, Kim, Bum-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014212/
https://ncbi.nlm.nih.gov/pubmed/20962085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01524-10
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