Hepatitis C Virus NS2 Protein Serves as a Scaffold for Virus Assembly by Interacting with both Structural and Nonstructural Proteins

Many aspects of the assembly of hepatitis C virus (HCV) remain incompletely understood. To characterize the role of NS2 in the production of infectious virus, we determined NS2 interaction partners among other HCV proteins during productive infection. Pulldown assays showed that NS2 forms complexes...

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Bibliografiske detaljer
Main Authors: Ma, Yinghong, Anantpadma, Manu, Timpe, Jennifer M., Shanmugam, Saravanabalaji, Singh, Sher M., Lemon, Stanley M., Yi, MinKyung
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014171/
https://ncbi.nlm.nih.gov/pubmed/20962101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01070-10
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