Genetic and Biochemical Determinants of Serum Concentrations of Monocyte Chemoattractant Protein-1, a Potential Neural Tube Defect Risk Factor

BACKGROUND: Women with the AA genotype at the (−2518) A>G promoter polymorphism of CCL-2, which encodes the potent pro-inflammatory chemokine monocyte chemoattractant protein 1 (MCP-1), may be at increased risk for having offspring affected by spina bifida. As the A allele at this locus has been...

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Hauptverfasser: Lu, Zhi-Yong, Morales, Megan, Khartulyari, Stephanie, Mei, Minghua, Murphy, Kristen M., Stanislawska-Sachadyn, Anna, Summers, Carolyn M., Huang, Yuehua, Von Feldt, Joan M, Blair, Ian A., Mitchell, Laura E., Whitehead, Alexander S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014088/
https://ncbi.nlm.nih.gov/pubmed/18937353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20507
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