The Sweet Pee Model for Sglt2 Mutation

Inhibiting renal glucose transport is a potential pharmacologic approach to treat diabetes. The renal tubular sodium-glucose transporter 2 (SGLT2) reabsorbs approximately 90% of the filtered glucose load. An animal model with sglt2 dysfunction could provide information regarding the potential long-t...

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Hauptverfasser: Ly, Joseph P., Onay, Tuncer, Sison, Karen, Sivaskandarajah, Gavasker, Sabbisetti, Venkata, Li, Lingli, Bonventre, Joseph V., Flenniken, Ann, Paragas, Neal, Barasch, Jon M., Adamson, S. Lee, Osborne, Lucy, Rossant, Janet, Schnermann, Jurgen, Quaggin, Susan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2011
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014040/
https://ncbi.nlm.nih.gov/pubmed/21209254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010080888
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