Adenylate Cyclase 6 Determines cAMP Formation and Aquaporin-2 Phosphorylation and Trafficking in Inner Medulla

Arginine vasopressin (AVP) enhances water reabsorption in the renal collecting duct by vasopressin V(2) receptor (V(2)R)-mediated activation of adenylyl cyclase (AC), cAMP-promoted phosphorylation of aquaporin-2 (AQP2), and increased abundance of AQP2 on the apical membrane. Multiple isoforms of ade...

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Autori principali: Rieg, Timo, Tang, Tong, Murray, Fiona, Schroth, Jana, Insel, Paul A., Fenton, Robert A., Hammond, H. Kirk, Vallon, Volker
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2010
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014019/
https://ncbi.nlm.nih.gov/pubmed/20864687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040409
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