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Mechanical Impact Induces Cartilage Degradation via Mitogen Activated Protein Kinases

OBJECTIVE: To determine the activation of MAP kinases in and around cartilage subjected to mechanical damage and to determine the effects of their inhibitors on impaction induced chondrocyte death and cartilage degeneration. DESIGN: The phosphorylation of MAP kinases was examined with confocal micro...

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Detalhes bibliográficos
Main Authors: Ding, Lei, Heying, Emily, Nicholson, Nathan, Stroud, Nicolas J., Homandberg, Gene A., Guo, Danping, Buckwalter, Joseph A., Martin, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013628/
https://ncbi.nlm.nih.gov/pubmed/20813194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2010.08.014
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