In VivoBiosafety Model to Assess the Risk of Adverse Events From Retroviral and Lentiviral Vectors

Serious adverse events in some human gene therapy clinical trials have raised safety concerns when retroviral or lentiviral vectors are used for gene transfer. We evaluated the potential for generating replication-competent retro-virus (RCR) and assessed the risk of occurrence of adverse events in a...

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Detalhes bibliográficos
Main Authors: Bauer, Gerhard, Dao, Mo A, Case, Scott S, Meyerrose, Todd, Wirthlin, Louisa, Zhou, Ping, Wang, Xiuli, Herrbrich, Phillip, Arevalo, Jesusa, Csik, Susie, Skelton, Dianne C, Walker, Jon, Pepper, Karen, Kohn, Donald B, Nolta, Jan A
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013368/
https://ncbi.nlm.nih.gov/pubmed/18461052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.93
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