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CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines
The highly conserved ESCRT-III complex is responsible for deformation and cleavage of membranes during endosomal trafficking and other cellular activities. In humans, dominant mutations in the ESCRT-III subunit CHMP2B cause fronto-temporal dementia (FTD). The decade-long process leading to this cort...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013364/ https://ncbi.nlm.nih.gov/pubmed/20699355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.068817 |
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