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The retinoid signaling pathway inhibits hematopoiesis and uncouples from the Hox genes during hematopoietic development

Retinoic acid (RA) is a well established inducer of Hox genes during development of neurectoderm, however effects of RA on Hox expression are poorly defined in mesoderm and not defined in the hematopoietic compartment. Both Hox genes and retinoid signaling have been suggested to modulate HSC self-re...

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Main Authors: Szatmari, Istvan, Iacovino, Michelina, Kyba, Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013318/
https://ncbi.nlm.nih.gov/pubmed/20681018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.484
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