Characterization of New Otic Enhancers of the Pou3f4 Gene Reveal Distinct Signaling Pathway Regulation and Spatio-Temporal Patterns

POU3F4 is a member of the POU-homedomain transcription factor family with a prominent role in inner ear development. Mutations in the human POU3F4 coding unit leads to X-linked deafness type 3 (DFN3), characterized by conductive hearing loss and progressive sensorineural deafness. Microdeletions fou...

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Main Authors: Robert-Moreno, Àlex, Naranjo, Silvia, de la Calle-Mustienes, Elisa, Gómez-Skarmeta, José Luis, Alsina, Berta
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2010
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013142/
https://ncbi.nlm.nih.gov/pubmed/21209840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015907
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