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Purging Deleterious Mutations under Self Fertilization: Paradoxical Recovery in Fitness with Increasing Mutation Rate in Caenorhabditis elegans

BACKGROUND: The accumulation of deleterious mutations can drastically reduce population mean fitness. Self-fertilization is thought to be an effective means of purging deleterious mutations. However, widespread linkage disequilibrium generated and maintained by self-fertilization is predicted to red...

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Detalhes bibliográficos
Main Authors: Morran, Levi T., Ohdera, Aki H., Phillips, Patrick C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013097/
https://ncbi.nlm.nih.gov/pubmed/21217820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014473
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