Turnover of BRCA1 Involves in Radiation-Induced Apoptosis

BACKGROUND: Germ-line mutations of the breast cancer susceptibility gene-1 (BRCA1) increase the susceptibility to tumorigenesis. The function of BRCA1 is to regulate critical cellular processes, including cell cycle progression, genomic integrity, and apoptosis. Studies on the regulation of BRCA1 ha...

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Autori principali: Liu, Weijun, Zong, Wenjun, Wu, George, Fujita, Takeo, Li, Wenqi, Wu, Judy, Wan, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013096/
https://ncbi.nlm.nih.gov/pubmed/21217819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014484
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