The CD40-Autophagy Pathway Is Needed for Host Protection Despite IFN-Γ-Dependent Immunity and CD40 Induces Autophagy via Control of P21 Levels

Autophagy degrades pathogens in vitro. The autophagy gene Atg5 has been reported to be required for IFN-γ-dependent host protection in vivo. However, these protective effects occur independently of autophagosome formation. Thus, the in vivo role of classic autophagy in protection conferred by adapti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Portillo, Jose-Andres C., Okenka, Genevieve, Reed, Erin, Subauste, Angela, Van Grol, Jennifer, Gentil, Katrin, Komatsu, Masaaki, Tanaka, Keiji, Landreth, Gary, Levine, Beth, Subauste, Carlos S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013095/
https://ncbi.nlm.nih.gov/pubmed/21217818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014472
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados