Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production

BACKGROUND: Dengue is now a leading cause of morbidity and mortality throughout the tropics. We conducted the first ex vivo study of dengue fever (DF) in African patients infected during the first Gabonese dengue virus 2 (DENV-2) outbreak in 2007, in order to investigate cytokine production, includi...

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Detalhes bibliográficos
Main Authors: Becquart, Pierre, Wauquier, Nadia, Nkoghe, Dieudonné, Ndjoyi-Mbiguino, Angélique, Padilla, Cindy, Souris, Marc, Leroy, Eric M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013083/
https://ncbi.nlm.nih.gov/pubmed/21167041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-356
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