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Insulin Signaling, Lifespan and Stress Resistance Are Modulated by Metabotropic GABA Receptors on Insulin Producing Cells in the Brain of Drosophila

Insulin-like peptides (ILPs) regulate growth, reproduction, metabolic homeostasis, life span and stress resistance in worms, flies and mammals. A set of insulin producing cells (IPCs) in the Drosophila brain that express three ILPs (DILP2, 3 and 5) have been the main focus of interest in hormonal DI...

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Detalhes bibliográficos
Main Authors: Enell, Lina E., Kapan, Neval, Söderberg, Jeannette A. E., Kahsai, Lily, Nässel, Dick R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012717/
https://ncbi.nlm.nih.gov/pubmed/21209905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015780
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