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Age and sex dependent changes in liver gene expression during the life cycle of the rat

BACKGROUND: Age- and sex-related susceptibility to adverse drug reactions and disease is a key concern in understanding drug safety and disease progression. We hypothesize that the underlying suite of hepatic genes expressed at various life cycle stages will impact susceptibility to adverse drug rea...

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Autori principali: Kwekel, Joshua C, Desai , Varsha G, Moland, Carrie L, Branham, William S, Fuscoe, James C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012673/
https://ncbi.nlm.nih.gov/pubmed/21118493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-675
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