HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway

HGAL is a germinal center (GC)–specific gene that negatively regulates lymphocyte motility and whose expression predicts improved survival of patients with diffuse large B-cell lymphoma (DLBCL) and classical Hodgkin lymphoma (cHL). We demonstrate that HGAL serves as a regulator of the RhoA signaling...

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Detalhes bibliográficos
Main Authors: Jiang, Xiaoyu, Lu, Xiaoqing, McNamara, George, Liu, Xiaofei, Cubedo, Elena, Sarosiek, Kristopher A., Sánchez-García, Isidro, Helfman, David M., Lossos, Izidore S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012539/
https://ncbi.nlm.nih.gov/pubmed/20844236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-281568
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