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The requirement for NKG2D in NK cell–mediated rejection of parental bone marrow grafts is determined by MHC class I expressed by the graft recipient

Natural killer (NK) cells provide a unique barrier to semiallogeneic bone marrow (BM) transplantation. In the setting where the parents donate to the F1 offspring, rejection of parental bone marrow occurs. This “hybrid resistance” is completely NK cell dependent, as T cells in the F1 recipient toler...

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Bibliografski detalji
Glavni autori: Beilke, Joshua N., Benjamin, Jonathan, Lanier, Lewis L.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012538/
https://ncbi.nlm.nih.gov/pubmed/20736452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-285031
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