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Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation

N-linked glycosylation modulates protein folding and stability through a variety of mechanisms. As such there is considerable interest in the development of general rules to predict the structural consequences of site-specific glycosylation and to understand how these effects can be exploited in the...

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Autors principals: Chen, Mark M., Bartlett, Alice I., Nerenberg, Paul S., Friel, Claire T., Hackenberger, Christian P. R., Stultz, Collin M., Radford, Sheena E., Imperiali, Barbara
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012502/
https://ncbi.nlm.nih.gov/pubmed/21148421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015356107
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