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Thalamocortical model for a propofol-induced α-rhythm associated with loss of consciousness

Recent data reveal that the general anesthetic propofol gives rise to a frontal α-rhythm at dose levels sufficient to induce loss of consciousness. In this work, a computational model is developed that suggests the network mechanisms responsible for such a rhythm. It is shown that propofol can alter...

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Autori principali: Ching, ShiNung, Cimenser, Aylin, Purdon, Patrick L., Brown, Emery N., Kopell, Nancy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012501/
https://ncbi.nlm.nih.gov/pubmed/21149695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017069108
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