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Attenuation of innate immunity by cytomegalovirus IL-10 establishes a long-term deficit of adaptive antiviral immunity

Human cytomegalovirus (HCMV) and many other pathogens exploit the IL-10 pathway, as part of their infectious cycle, either through their own encoded IL-10 (hcmvIL-10 for HCMV) or manipulation of the cellular IL-10 signaling cascade. Based on the in vitro demonstrations of its pleiotropic and cell ty...

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Sonraí Bibleagrafaíochta
Main Authors: Chang, W. L. William, Barry, Peter A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012498/
https://ncbi.nlm.nih.gov/pubmed/21149711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013794108
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